Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 857
interventional 769
Observational 82
Registry 6

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 302
Drug|Radiation 87
Drug|placebo 32
Biological 31
Drug|Other 31
Biological|Drug 29
Drug|Procedure|Radiation 25
Radiation 23
Procedure 20
Other 18
Drug|Procedure 15
Drug|Other|Radiation 13
Biological|Drug|Other 12
Device 12
Drug|Other|Procedure|Radiation 9
Biological|Other 8
Biological|Drug|Radiation 7
Combination Product 6
Biological|Drug|Other|Radiation 5
Biological|Other|Radiation 5
Drug|Other|Procedure 5
Biological|Drug|placebo 4
Dietary Supplement 4
Procedure|Radiation 4
Combination Product|Drug 3
Device|Drug 3
Diagnostic Test 3
Drug|Other|placebo 3
Drug|placebo|Radiation 3
Other|Procedure 3
Behavioral|Other 2
Behavioral|Radiation 2
Biological|Drug|Other|placebo 2
Biological|Drug|Procedure 2
Biological|Other|Procedure 2
Biological|Other|Procedure|Radiation 2
Biological|placebo 2
Biological|Radiation 2
Dietary Supplement|placebo 2
Behavioral 1
Behavioral|Drug|placebo 1
Behavioral|placebo 1
Biological|Diagnostic Test 1
Biological|Dietary Supplement|Drug|Procedure|Radiation 1
Biological|Drug|Other|placebo|Procedure 1
Biological|Drug|Other|Procedure|Radiation 1
Biological|Drug|placebo|Radiation 1
Biological|Drug|Procedure|Radiation 1
Biological|Genetic 1
Biological|Procedure 1
Biological|Procedure|Radiation 1
Combination Product|Other|Procedure 1
Device|Drug|Procedure 1
Device|Drug|Radiation 1
Device|placebo 1
Diagnostic Test|Drug|Radiation 1
Dietary Supplement|Other 1
Dietary Supplement|Procedure 1
Drug|Genetic|Other|Procedure|Radiation 1
Drug|Other|placebo|Procedure 1
Drug|Other|placebo|Radiation 1
Drug|placebo|Procedure 1
Genetic 1
Other|Radiation 1
placebo|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 362
China 111
France 33
Canada 23
NA 19
Korea, Republic of 16
Taiwan 14
United Kingdom 12
Germany 10
United States|Canada 9
Netherlands 8
Brazil 6
Italy 6
Belgium 5
Spain 5
Austria 4
India 3
United States|Puerto Rico 3
Denmark 2
Egypt 2
Israel 2
Japan 2
Singapore 2
Switzerland 2
United States|China 2
United States|France|Spain 2
Argentina 1
Argentina|Cuba|India|Indonesia|Pakistan|Philippines|South Africa|Thailand|Uruguay 1
Australia 1
Australia|Belgium|France|Germany|Netherlands|Poland|Switzerland 1
Australia|Canada 1
Australia|Cuba|Egypt|India|Indonesia|Korea, Republic of|Malaysia|Philippines|Saudi Arabia|Singapore|South Africa|Taiwan|Thailand 1
Australia|New Zealand 1
Australia|Russian Federation 1
Austria|Belgium|Czech Republic|France|Germany|Hungary|Italy|Netherlands|Poland|Portugal|Russian Federation|Slovakia|Spain|Sweden|Switzerland|Ukraine|United Kingdom 1
Austria|Belgium|France|Germany|Hungary|Italy|Poland|Spain|Switzerland 1
Belarus|Hungary|Poland|Russian Federation|Ukraine 1
Belgium|Brazil|Canada|Estonia|France|Hungary|Lithuania|Poland|Russian Federation|Serbia|Sweden|United Kingdom 1
Belgium|Canada|Spain 1
Belgium|France|Germany 1
Belgium|France|Italy|United Kingdom 1
Belgium|Italy 1
Belgium|Luxembourg 1
Belgium|United States|Australia 1
China|Korea, Republic of 1
Czech Republic 1
France|Germany|Spain 1
France|Greece|India|Peru|Spain 1
France|Italy|Netherlands|Spain|United Kingdom 1
France|Monaco 1
France|Spain 1
France|Switzerland 1
France|United Kingdom 1
Germany|Italy|Spain 1
Germany|United States|Australia|Austria|Brazil|France|Greece|Ireland|Israel|Italy|Japan|Korea, Republic of|Mexico|Poland|Spain|Switzerland|Taiwan|United Kingdom 1
Germany|United States|Australia|France|Spain 1
Greece 1
Indonesia 1
Japan|Korea, Republic of 1
Korea, Republic of|United Kingdom 1
Lithuania 1
Mexico 1
Pakistan 1
Palestinian Territory, occupied 1
Poland 1
Russian Federation 1
Saudi Arabia 1
Spain|United States|Belgium|Germany|Italy|United Kingdom 1
Sweden 1
Taiwan|United States|Belgium|China|France|Germany|Italy|Japan|Korea, Republic of|Spain|United Kingdom 1
Thailand 1
United Kingdom|United States|Belgium|Denmark|Sweden 1
United States|Argentina|Australia|Austria|Belgium|Brazil|Canada|Chile|Colombia|France|Germany|Hungary|Israel|Japan|Korea, Republic of|Poland|Portugal|Russian Federation|Spain|Switzerland|Taiwan|Ukraine|United Kingdom 1
United States|Argentina|Australia|Austria|Belgium|Brazil|Canada|France|Germany|Greece|Guadeloupe|Hungary|Israel|Italy|Russian Federation|Réunion|South Africa|Spain|Switzerland|Uruguay 1
United States|Argentina|Australia|Austria|Brazil|Canada|France|Germany|Japan|Korea, Republic of|Mexico|New Zealand|Poland|Romania|Russian Federation|Spain|Taiwan|Turkey|Ukraine|United Kingdom 1
United States|Argentina|Australia|Belgium|Brazil|Bulgaria|Chile|Croatia|Czechia|France|Georgia|Germany|Hungary|Israel|Italy|Japan|Korea, Republic of|Poland|Romania|Russian Federation|Serbia|Spain|Taiwan|Ukraine 1
United States|Argentina|Australia|Belgium|Brazil|Canada|Croatia|Czech Republic|Estonia|Greece|India|Israel|Italy|Latvia|Lithuania|Malaysia|Netherlands|Norway|Russian Federation|Slovenia|South Africa|Spain|Sweden|Thailand|United Kingdom 1
United States|Argentina|Australia|Brazil|Canada|Colombia|France|Germany|Greece|Hungary|Israel|Italy|Mexico|Norway|Portugal|Romania|Russian Federation|Spain|United Kingdom 1
United States|Argentina|Australia|Canada|France|Germany|Greece|Ireland|Israel|Korea, Republic of|Netherlands|Norway|Poland|Portugal|Romania|Russian Federation|Spain|Sweden|Taiwan|United Kingdom 1
United States|Argentina|Austria|Belgium|Brazil|Czechia|Denmark|France|Germany|Greece|Israel|Italy|Japan|Mexico|Russian Federation|South Africa|Spain|Sweden|Switzerland 1
United States|Argentina|Belgium|Brazil|Canada|Chile|Czechia|Finland|France|Ireland|Italy|Mexico|Netherlands|Norway|Romania|Russian Federation|South Africa|Spain|Sweden|Turkey|United Kingdom 1
United States|Argentina|Brazil|Canada|France|Germany|Hong Kong|Italy|Japan|Korea, Republic of|Netherlands|Spain|Switzerland|Taiwan|United Kingdom 1
United States|Australia 1
United States|Australia|Austria|Belgium|Brazil|Canada|Colombia|Czechia|France|Germany|Israel|Italy|Japan|Korea, Republic of|Netherlands|New Zealand|Poland|Spain|Taiwan|Turkey|United Kingdom 1
United States|Australia|Austria|Belgium|Canada|France|Greece|Italy|Spain|Switzerland|United Kingdom 1
United States|Australia|Austria|Canada|Turkey|Hungary|Italy|Japan|Korea, Republic of|Poland|Portugal|Spain|Taiwan|United Kingdom 1
United States|Australia|Belgium|Brazil|Canada|China|France|Germany|Hungary|India|Italy|Japan|Korea, Republic of|Poland|Portugal|Russian Federation|South Africa|Spain|Taiwan|Thailand|Turkey|Ukraine|United Kingdom 1
United States|Australia|Belgium|Brazil|Canada|France|Germany|Greece|Ireland|Italy|Japan|New Zealand|Poland|Russian Federation|Spain|United Kingdom 1
United States|Australia|Belgium|Bulgaria|France|Germany|Hungary|Italy|Romania|Spain|United Kingdom 1
United States|Australia|Belgium|Canada|Czechia|France|Georgia|Germany|Hungary|Israel|Korea, Republic of|Malaysia|Spain|Taiwan|United Kingdom 1
United States|Australia|Belgium|China|Czechia|France|Germany|Italy|Japan|Korea, Republic of|Poland|Romania|Russian Federation|Spain|Taiwan|United Kingdom 1
United States|Australia|Canada 1
United States|Australia|Canada|France|Germany|Israel|Mexico|Norway|Spain|United Kingdom 1
United States|Australia|France|Italy|Japan 1
United States|Australia|Korea, Republic of|Taiwan 1
United States|Austria|Belarus|Bosnia and Herzegovina|Canada|Croatia|France|Hungary|India|Israel|Italy|Malaysia|Poland|Romania|Russian Federation|Serbia|Spain|Sri Lanka|Taiwan|Thailand|Turkey|Ukraine|United Kingdom 1
United States|Austria|Chile|Colombia|Czech Republic|Germany|Israel|Italy|Peru|Portugal|Slovakia 1
United States|Austria|Israel|Korea, Republic of|Norway|Spain 1
United States|Belgium 1
United States|Belgium|Canada|Czechia|France|Georgia|Germany|Hungary|Israel|Korea, Republic of|Malaysia|Spain|Taiwan|United Kingdom 1
United States|Belgium|Canada|France|Germany|Greece|Hungary|Italy|Poland|Russian Federation|Slovenia|Spain|United Kingdom 1
United States|Belgium|Canada|Hong Kong|Korea, Republic of|Singapore|Spain|Taiwan|United Kingdom 1
United States|Belgium|Canada|Spain 1
United States|Belgium|Czech Republic|France|Hungary|Poland|Slovakia|United Kingdom 1
United States|Belgium|Czech Republic|Germany|India|Poland|Serbia|Taiwan 1
United States|Belgium|Czechia|France|Germany|Hungary|Italy|Netherlands|Spain|United Kingdom 1
United States|Belgium|France|Germany|Greece|Italy|Korea, Republic of|Netherlands|Spain|United Kingdom 1
United States|Belgium|France|Italy|Spain|United Kingdom 1
United States|Belgium|France|Spain 1
United States|Belgium|France|Spain|United Kingdom 1
United States|Bulgaria|Hungary|Romania 1
United States|Canada|China 1
United States|Canada|France|Germany|Italy|Spain|United Kingdom 1
United States|Canada|France|Japan|Korea, Republic of|Poland|Spain|Taiwan|Turkey 1
United States|Canada|Ireland|Saudi Arabia 1
United States|Canada|Korea, Republic of|Spain|Taiwan 1
United States|China|Japan|Singapore 1
United States|China|Singapore 1
United States|Czechia|Hungary|Italy|Japan|Korea, Republic of|Mexico|Poland|Romania|Russian Federation|Serbia|Slovakia|Spain|Taiwan|Ukraine 1
United States|France 1
United States|France|Germany|Israel|Netherlands|Spain 1
United States|France|Italy|Japan|Korea, Republic of|Poland|Russian Federation|Spain|Taiwan|Turkey 1
United States|France|Korea, Republic of|Spain|Turkey 1
United States|France|Taiwan|United Kingdom 1
United States|Hungary|Poland|Russian Federation|Serbia|Spain|Ukraine 1
United States|Japan|Australia|Austria|Belgium|Canada|China|France|Germany|Greece|Hungary|Ireland|Israel|Italy|Korea, Republic of|Poland|Portugal|Russian Federation|Spain|Switzerland|Taiwan|United Kingdom 1
United States|Japan|Korea, Republic of|Spain|Taiwan 1
United States|Korea, Republic of|Ukraine|United Kingdom 1
United States|Netherlands|Spain 1
United States|Puerto Rico|South Africa 1

Sites per Study

Site_count Study_Count
1 445
2 48
3 28
4 25
5 27
6 18
7 11
8 14
9 10
10 8
11 7
12 4
13 9
14 7
15 2
16 4
17 3
18 3
19 1
20 7
21 3
22 1
23 5
24 3
25 2
26 1
28 1
29 2
30 2
33 2
34 1
35 3
36 1
37 1
39 1
40 1
42 2
48 2
49 2
51 1
53 3
55 1
58 1
59 1
60 1
64 1
69 1
70 1
71 1
77 1
82 1
91 2
101 2
103 1
104 1
105 1
108 2
110 1
124 1
125 1
131 1
133 1
149 1
151 1
160 1
161 1
164 1
169 1
189 1
194 1
220 1
222 1
224 1
228 1
232 1
272 1
308 1
362 1
367 1
432 1
508 2
789 1
931 1
938 1
1498 1

Phase

Phase Study_Count
Phase 2 357
Phase 1 151
N/A 86
Phase 3 77
Phase 1/Phase 2 69
Early Phase 1 11
Phase 2/Phase 3 11
Phase 4 7

Number of Arms

Number_of_Arms Count_of_Studies
1 379
2 267
3 44
4 27
5 9
6 3
7 2
8 3
10 2
11 2
15 1
NA 30

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 5.00000 1.0000 1.00000 1.00000 2.00000 30.00 50.0000 19.0000
1st Qu. 15.50000 30.0000 18.00000 30.00000 32.00000 250.00 210.0000 27.0000
Median 16.00000 72.0000 30.00000 45.00000 50.00000 410.50 357.0000 74.0000
Mean 29.54545 754.1047 49.05298 69.91304 78.56303 390.30 409.3553 227.5714
3rd Qu. 46.00000 209.0000 47.50000 70.00000 94.00000 556.75 516.7500 246.0000
Max. 70.00000 33948.0000 360.00000 403.00000 818.00000 711.00 1131.0000 954.0000

Trial Group Type

group_type Group_Count
Experimental 1013
Active Comparator 179
Placebo Comparator 55
Other 43
NA 30
No Intervention 19
Sham Comparator 2

Intervention Model

intervention_model Study_Count
Single Group Assignment 412
Parallel Assignment 305
Sequential Assignment 34
Factorial Assignment 10
Crossover Assignment 4
NA 4

Primary Purpose

primary_purpose Study_Count
Treatment 694
Supportive Care 19
Diagnostic 18
Prevention 15
Other 8
Screening 7
NA 5
Health Services Research 2
Basic Science 1

Observational Studies

Studies by Country

Country Study_Count
United States 24
France 10
Canada 6
NA 6
United Kingdom 4
Denmark 3
Brazil 2
China 2
Egypt 2
Germany 2
Netherlands 2
Belgium 1
Belgium|Netherlands 1
Czech Republic 1
Greece 1
Israel 1
Italy 1
Kenya 1
Korea, Republic of 1
Malawi 1
Mexico 1
Netherlands|Switzerland 1
Singapore 1
Spain 1
Sweden 1
Switzerland 1
Taiwan 1
Thailand 1
United States|Germany|Greece|Italy|Japan|Korea, Republic of|Spain 1
United States|Puerto Rico 1

Sites per Study

Site_count Study_Count
1 70
2 5
3 1
4 2
14 1
18 1
33 1
187 1

Enrollment Metrics

Measure Observational
Min 1.000
1st Qu 34.500
Median 83.000
Mean 162.561
3rd Qu 173.000
Max 1500.000

Observation Model

observational_model Study_Count
Cohort 42
Case-Only 19
Case-Control 8
Case Control 5
Other 4
NA 4

Time Perspective

time_perspective Study_Count
Prospective 58
Retrospective 15
Cross-Sectional 6
NA 2
Other 1

Registries

Studies by Country

Country Study_Count
China 1
Denmark 1
France 1
Italy 1
Spain 1
Taiwan 1

Sites per Study

Site_count Study_Count
1 5
15 1

Enrollment Metrics

Measure Registries
Min 1.00
1st Qu 69.75
Median 430.50
Mean 1282.50
3rd Qu 770.25
Max 6000.00

Registry Model

observational_model Study_Count
Cohort 4
Case-Control 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 6

Follow-up

target_duration Study_Count
1 Day 1
1 Year 1
12 Months 1
25 Years 1
3 Years 1
4 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03418909 Functional Outcome After Treatment for Oropharyngeal Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03418909 Active, not recruiting Rigshospitalet, Denmark 2020-03-31
NCT03357107 Local Control After Robot-assisted Supraglottic Laryngectomy https://ClinicalTrials.gov/show/NCT03357107 Completed Hospices Civils de Lyon 2017-02-28
NCT03325738 Cetuximab for Unresectable Cutaneous Squamous Cell Carcinoma - A National Retrospective Study https://ClinicalTrials.gov/show/NCT03325738 Completed Centre Antoine Lacassagne 2017-06-30
NCT03304132 The Oral Microbiome and Upper Aerodigestive Squamous Cell Cancer https://ClinicalTrials.gov/show/NCT03304132 Completed NYU Langone Health 2010-12-01
NCT03225157 Hearing Loss and the Effects of Statin Drugs in People With Head and Neck Squamous Cell Carcinoma Treated With Cisplatin Chemoradiation https://ClinicalTrials.gov/show/NCT03225157 Completed National Institutes of Health Clinical Center (CC) 2020-02-28
NCT03162042 Role of Myostatin, Activin A and Follistatin Cachexia of ENT Cancers https://ClinicalTrials.gov/show/NCT03162042 Completed University Hospital, Clermont-Ferrand 2016-02-29
NCT03161613 Study to Assess the Safety of Nivolumab in the Treatment of Metastatic Melanoma, Lung Cancer, Renal Cancer, Squamous Cell Carcinoma of the Head and Neck, and Chronic Hodgkin Lymphoma in Adults in Mexico https://ClinicalTrials.gov/show/NCT03161613 Recruiting Bristol-Myers Squibb 2019-04-01
NCT03160209 HIV and Other Risk Factors for Esophageal Squamous Cell Carcinoma in Malawi https://ClinicalTrials.gov/show/NCT03160209 Recruiting UNC Lineberger Comprehensive Cancer Center 2020-07-31
NCT03114163 Observational Study of Nivolumab in Patients in Germany With Squamous Cell Carcinoma of the Head and Neck Progressing on or After Platinum-Based Therapy https://ClinicalTrials.gov/show/NCT03114163 Recruiting Bristol-Myers Squibb 2024-07-01
NCT03109457 Hepatitis C Virus Detection in Oral Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03109457 Completed Cairo University 2018-02-07
NCT03053661 Immune Response Evaluation to Curative Conventional Therapy https://ClinicalTrials.gov/show/NCT03053661 Active, not recruiting University of Ulm 2020-08-31
NCT02879968 Serum Squamous Cell Carcinoma Antigen Level and Tumor Volume in Head and Neck Cancer https://ClinicalTrials.gov/show/NCT02879968 Completed Prince of Songkla University 2018-08-31
NCT02852343 One-step Nucleic Acid Amplification for Detecting Lymph Node Metastasis of Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT02852343 Completed Rennes University Hospital 2016-12-21
NCT02778191 Comparison of Concomitant Cisplatin Versus Carboplatin and 5-fluorouracil With Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT02778191 Completed University Medical Center Groningen 2017-03-31
NCT02672254 New Strategies Against Cutaneous Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT02672254 Completed Corporacion Parc Tauli 2016-01-31
NCT02663583 Intensity-Modulated Proton Therapy (IMPT) or TransOral Robotic Surgery (TORS) for the Treatment of Low-Risk Oropharynx Squamous Cell https://ClinicalTrials.gov/show/NCT02663583 Recruiting M.D. Anderson Cancer Center 2020-12-31
NCT02628379 Outcomes of FoundationOne Directed Therapy in Cancer of Unknown Primary https://ClinicalTrials.gov/show/NCT02628379 Completed Foundation Medicine 2017-03-31
NCT03148665 Saliva-based Detection of CD44 https://ClinicalTrials.gov/show/NCT03148665 Active, not recruiting University of California, San Diego 2019-04-10
NCT02379039 Multimodal Monitoring of Radiotherapy Response in Squamous Cell Cancer https://ClinicalTrials.gov/show/NCT02379039 Recruiting Umeå University 2021-05-31
NCT02549638 Identification of Prognostic Biomarkers for Progression of Invasive Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT02549638 Recruiting Mayo Clinic 2020-08-31
NCT02543476 SUPREME-HN A Retrospective Cohort Study of PD-L1 in Recurrent and Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN) https://ClinicalTrials.gov/show/NCT02543476 Completed AstraZeneca 2016-11-14
NCT02279459 Dual-Energy CT in Patients With Head and Neck Squamous Cell Carcinomas https://ClinicalTrials.gov/show/NCT02279459 Completed Ottawa Hospital Research Institute 2018-10-01
NCT02245100 Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer https://ClinicalTrials.gov/show/NCT02245100 Recruiting Thomas Jefferson University 2020-07-31
NCT02242916 State of the Art Photon Therapy Versus Particle Therapy for Recurrent Head & Neck Tumors; a Planning Study https://ClinicalTrials.gov/show/NCT02242916 Completed Maastricht Radiation Oncology 2015-10-31
NCT02147418 Exosome Testing as a Screening Modality for Human Papillomavirus-Positive Oropharyngeal Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT02147418 Recruiting New Mexico Cancer Care Alliance 2021-01-31
NCT02149602 A Phase II Study of Parotid-gland Sparing IMRT in Patients With Midline Tumour of the Head and Neck https://ClinicalTrials.gov/show/NCT02149602 Completed Royal Marsden NHS Foundation Trust 2011-11-30
NCT02145416 ART: Anal Squamous Cell Carcinoma: Investigation of Functional Imaging During chemoRadioTherapy https://ClinicalTrials.gov/show/NCT02145416 Completed University of Oxford 2017-12-08
NCT02139020 Collection of Plasma Samples for Squamous Cell Carcinoma of the Head and Neck Patients https://ClinicalTrials.gov/show/NCT02139020 Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2023-01-31
NCT02095912 Aggressive Squamous Cell Carcinoma in Organ Transplant Recipients https://ClinicalTrials.gov/show/NCT02095912 Completed University of Zurich 2015-11-30
NCT02003482 Prospective Trial of Serial CT Imaging for Evaluation of Dosimetric/Volumetric Changes During IMRT for Head/Neck Cancer https://ClinicalTrials.gov/show/NCT02003482 Completed University of Miami 2018-03-26
NCT01976468 Metastases of Cutaneous Squamous Cell Carcinoma in Organ Transplant Recipients. The “SCOPE-ITSCC Metastases Study” https://ClinicalTrials.gov/show/NCT01976468 Active, not recruiting University of Zurich 2023-01-31
NCT01827956 Role of FCγRIIIA and FCγRIIA Receptor Polymorphisms https://ClinicalTrials.gov/show/NCT01827956 Completed Institut Bergonié 2011-06-30
NCT01783158 Chromoendoscopy to Detect Early Synchronous Second Primary Esophageal Carcinoma https://ClinicalTrials.gov/show/NCT01783158 Completed University Hospital Ostrava 2012-11-30
NCT01540695 Does Cryofixation of Skin Specimens Affect Quality of Subsequent Formalin Fixed Paraffin Embedded H and E Histology https://ClinicalTrials.gov/show/NCT01540695 Completed Abramson Cancer Center of the University of Pennsylvania 2013-01-31
NCT01500954 Microarray Analysis of microRNA Expression Profiles in Cutaneous Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT01500954 Completed Ruhr University of Bochum 2011-12-31
NCT01472419 Prognostic Factor Analysis in Metastatic Esophageal Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT01472419 Completed Samsung Medical Center 2012-12-31
NCT01358097 Role of Immune Activation in Response of Head and Neck Squamous Cell Carcinoma to Therapy https://ClinicalTrials.gov/show/NCT01358097 Completed Icahn School of Medicine at Mount Sinai 2013-09-30
NCT01321892 Ex Vivo Multimodal Imaging of Upper Aerodigestive Epithelium https://ClinicalTrials.gov/show/NCT01321892 Completed Icahn School of Medicine at Mount Sinai 2012-05-31
NCT04260074 Epigenetic Changes in Head and Neck Cancer https://ClinicalTrials.gov/show/NCT04260074 Recruiting Aalborg University Hospital 2020-07-31
NCT04224389 IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas https://ClinicalTrials.gov/show/NCT04224389 Recruiting Gustave Roussy, Cancer Campus, Grand Paris 2023-06-30
NCT04224896 Narrow-Band Imaging (NBI) Versus Lugol Chromoendoscopy in the Detection of Oesophagus Squamous Cell Carcinoma in High Risk Population https://ClinicalTrials.gov/show/NCT04224896 Completed Hôpital Edouard Herriot 2011-03-01
NCT04218136 Cetuximab Therapeutic Drug Monitoring in Squamous Cell Carcinoma Head and Neck Cancer Patients: Determination of the Predictive Value Exposure Levels Through a Single Arm Multicentric Study https://ClinicalTrials.gov/show/NCT04218136 Recruiting Assistance Publique Hopitaux De Marseille 2022-04-28
NCT04201002 Surgery Plus Intraoperative Radiotherapy as Treatment for Squamous Cell Carcinoma Over Pilonidal Disease. https://ClinicalTrials.gov/show/NCT04201002 Completed Hospital Provincial de Castellon 2019-10-11
NCT04199832 To Compare the Effect of Different Nutritional Pathways on Improving Nutritional Status of Esophageal Cancer Patients Undergoing Chemoradiotherapy https://ClinicalTrials.gov/show/NCT04199832 Recruiting Tianjin Medical University Cancer Institute and Hospital 2020-12-31
NCT04183218 Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes in Non-metastatic, Non-recurrent Lung and Esophageal Cancer Patients https://ClinicalTrials.gov/show/NCT04183218 Recruiting Mayo Clinic 2021-09-23
NCT04151134 Evaluation of Tongue Base MucOsectomy & Step sErial Sectioning https://ClinicalTrials.gov/show/NCT04151134 Recruiting Royal Marsden NHS Foundation Trust 2020-11-01
NCT04099290 Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT04099290 Recruiting UNC Lineberger Comprehensive Cancer Center 2020-09-30
NCT04086849 Analysis of Patterns of Recurrence in Head and Neck Cancer Using Clinicopathomic Markers https://ClinicalTrials.gov/show/NCT04086849 Recruiting Sunnybrook Health Sciences Centre 2024-12-30
NCT04050761 A Study of Nivolumab in Patients With Head and Neck Cancer. https://ClinicalTrials.gov/show/NCT04050761 Recruiting Bristol-Myers Squibb 2024-06-26
NCT04003025 Body Composition and Prognosis in Head and Neck Squamous Cell Carcinoma (HNSCC) https://ClinicalTrials.gov/show/NCT04003025 Recruiting Instituto do Cancer do Estado de São Paulo 2020-07-31
NCT03953443 Expression & Epigenetic Silencing of MicroRNA for Predicting Therapeutic Response and Prognosis of HPV-negative HNSCC https://ClinicalTrials.gov/show/NCT03953443 Enrolling by invitation New Mexico Cancer Care Alliance 2025-12-31
NCT03938012 Evaluating Mutations in MET and TP53 Among Patients Diagnosed With Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03938012 Recruiting National University Hospital, Singapore 2021-10-31
NCT03877159 Analysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03877159 Recruiting Guy’s and St Thomas’ NHS Foundation Trust 2020-01-30
NCT03836105 CemiplimAb Survivorship Epidemiology https://ClinicalTrials.gov/show/NCT03836105 Recruiting Regeneron Pharmaceuticals 2023-12-31
NCT03759756 Artificial Intelligence for Early Diagnosis of Esophageal Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03759756 Completed Shandong University 2020-03-01
NCT03727594 Radioguided Selective Neck Dissection for Staging and Treatment of Oral Cavity and Oropharyngeal Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03727594 Recruiting University Hospital of Ferrara 2020-01-31
NCT03712566 Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy https://ClinicalTrials.gov/show/NCT03712566 Active, not recruiting University Health Network, Toronto 2022-10-31
NCT03554967 Toluidine Blue Versus Frozen Sections for Assessment of Tumor Margins in Oral Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03554967 Completed Cairo University 2019-06-03
NCT03529604 Salivary Ap4A, SCCA, TROP2 in Oral Cancer Patients https://ClinicalTrials.gov/show/NCT03529604 Active, not recruiting University of Zagreb 2020-04-01
NCT03467529 Evaluation of Full-field Coherence Tomography for ex Vivo Staging and Assessment of Superficial Esophageal Squamous Carcinoma: a Pilot Study https://ClinicalTrials.gov/show/NCT03467529 Recruiting Nantes University Hospital 2021-04-30
NCT01179360 Combined FDG PET/CT Imaging in Response Evaluation After Radiochemotherapy in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) https://ClinicalTrials.gov/show/NCT01179360 Completed University Hospital, Antwerp 2015-12-31
NCT01104714 Pharmacogenetic Response to Chemotherapy Induction for ORL Cancers https://ClinicalTrials.gov/show/NCT01104714 Completed Centre Hospitalier Universitaire de Nīmes 2014-07-31
NCT01080066 A Post Marketing Surveillance Study of Cetuximab in Patients With Squamous Cell Carcinoma of Head and Neck (SCCHN) https://ClinicalTrials.gov/show/NCT01080066 Completed Merck KGaA, Darmstadt, Germany 2013-12-31
NCT01075828 Prospective, Post Marketing Surveillance Study On Erbitux® (Cetuximab) in Patients With Locally Advanced or Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck in Korea https://ClinicalTrials.gov/show/NCT01075828 Completed Merck KGaA, Darmstadt, Germany 2014-07-31
NCT01043328 Human Papillomavirus on Oral Tissue, Saliva and Serum https://ClinicalTrials.gov/show/NCT01043328 Completed UPECLIN HC FM Botucatu Unesp 2010-01-31
NCT01017224 DAHANCA 24: Prognostic Value of 18F-FAZA in Head and Neck Squamous Cell Carcinoma (HNSCC) https://ClinicalTrials.gov/show/NCT01017224 Completed University of Aarhus 2012-05-31
NCT00897442 Collecting Tumor Samples From Patients With Gynecological Tumors https://ClinicalTrials.gov/show/NCT00897442 Completed Gynecologic Oncology Group 2016-01-31
NCT00901173 A Pilot for a Case-Control Study of Esophageal Squamous Cell Carcinoma in Western Kenya https://ClinicalTrials.gov/show/NCT00901173 Completed National Institutes of Health Clinical Center (CC) 2020-04-20
NCT00875381 Analysis of Melanocytes (Pigment Cells) in Sun-Exposed Skin https://ClinicalTrials.gov/show/NCT00875381 Completed Mayo Clinic 2007-12-31
NCT00868725 Detecting Lesions in the Oral Cavity With Thermal Imaging https://ClinicalTrials.gov/show/NCT00868725 Completed Sheba Medical Center 2009-06-30
NCT03759730 Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03759730 Completed University Health Network, Toronto 2018-11-28
NCT03652142 Predictive Biomarkers for Response to Nivolumab in Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03652142 Recruiting Attikon Hospital 2020-05-01
NCT00793169 Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery https://ClinicalTrials.gov/show/NCT00793169 Completed Northwestern University 2008-07-31
NCT00662662 Sexual Behavior in Head and Neck Cancer Patients https://ClinicalTrials.gov/show/NCT00662662 Active, not recruiting M.D. Anderson Cancer Center 2022-05-31
NCT00620139 Proximal Molecular Effects of Concurrent Chemoradiotherapy on Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT00620139 Completed Memorial Sloan Kettering Cancer Center 2013-10-31
NCT00592371 Head and Neck Cancer Screening and Serum Repository https://ClinicalTrials.gov/show/NCT00592371 Completed University of Arkansas 2012-09-30
NCT00530283 PET-CT for Squamous Cell Carcinoma (SCC) of the Neck Nodes Unknown Primary Malignancy https://ClinicalTrials.gov/show/NCT00530283 Completed AHS Cancer Control Alberta 2010-07-31
NCT00195299 Study Evaluating Temsirolimus in Advanced Stage Squamous Cell Carcinoma of the Head & Neck https://ClinicalTrials.gov/show/NCT00195299 Completed Wyeth is now a wholly owned subsidiary of Pfizer NA
NCT00124488 Comparison of Tomotherapy Versus Intensity-modulated Step-and-shoot and Conventional Radiation Treatment Plans for Patients With Locally-advanced Squamous Cell Carcinoma of the Cervix https://ClinicalTrials.gov/show/NCT00124488 Completed AHS Cancer Control Alberta NA
NCT00011492 Patient Evaluation for Head and Neck Surgery Branch Studies https://ClinicalTrials.gov/show/NCT00011492 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00836342 Correlation Between Skin Carotenoid Levels and Previous History of Skin Cancer https://ClinicalTrials.gov/show/NCT00836342 Completed Massachusetts General Hospital 2012-01-31
NCT00001603 The Effects of Upper Airway and Digestive Tract Tumors on the Immune System https://ClinicalTrials.gov/show/NCT00001603 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03160495 Functional ImaGing of Heterogeneity in Head and Neck Tumors - Validation From Surgical Specimens https://ClinicalTrials.gov/show/NCT03160495 Completed Rigshospitalet, Denmark 2018-09-30
NCT02310503 Spanish Registry of Mohs Surgery https://ClinicalTrials.gov/show/NCT02310503 Completed Fundación Academia Española de Dermatología 2020-02-29
NCT03917524 Feasibility of CTCs Isolation for Transcriptomes and Genome Wide Associated Analysis in Post-OP High Risk OSCC Patients. https://ClinicalTrials.gov/show/NCT03917524 Recruiting Chang Gung Memorial Hospital 2019-07-31
NCT03786601 Postmenopausal Women With Vaginal Microbiota https://ClinicalTrials.gov/show/NCT03786601 Recruiting Peking Union Medical College Hospital 2019-12-01
NCT03614936 Study of a Simplified Geriatric Evaluation Performed by Oncologists Prior to Cancer Treatment by Radiotherapy or Chemotherapy in Subjects Aged 70 Years or Older With Inoperable Squamous Cell Cancer of the Head and Neck https://ClinicalTrials.gov/show/NCT03614936 Recruiting Gustave Roussy, Cancer Campus, Grand Paris 2019-06-30
NCT03546998 Epidermoid Cancer Development in Esophageal Achalasia https://ClinicalTrials.gov/show/NCT03546998 Recruiting University of Bologna 2025-12-31